HBV Basic Science
Gut Microbes May Play a Role in Age-Related Hepatitis B Virus Clearance
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- Category: HBV Basic Science
- Published on Thursday, 05 February 2015 00:00
- Written by Liz Highleyman
Treating adult mice with antibiotics to wipe out their intestinal microbiota made them unable to naturally clear hepatitis B virus (HBV), so they became more like young mice that developed chronic infection, according to a report in the February 2 Proceedings of the National Academy of Sciences. The researchers also showed that mice lacking toll-like receptor 4 (TLR4) cleared HBV regardless of age.
Novel Lab Technique May Aid Study of New Hepatitis B Treatments
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- Category: HBV Basic Science
- Published on Thursday, 28 August 2014 00:00
- Written by MIT
A laboratory model of the hepatitis B virus (HBV) lifecycle using a stem cell technique that maintains the virus in liver cells may help researchers d
evelop new treatments for the disease, according to a report in the August 4 advance edition of the Proceedings of the National Academy of Sciences.
Researchers Discover Structure of Hepatitis B Antigen that Interferes with Immune Response
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- Category: HBV Basic Science
- Published on Tuesday, 08 January 2013 00:00
- Written by NIH
Researchers from the University of Oxford and the U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases have determined the crystal structure of the hepatitis B "e" antigen (HBeAg), which plays a role in immune tolerance and chronic hepatitis B virus (HBV) infection, according to a study published in the January 8, 2013, issue of the journal Structure. These findings may aid the development of new therapies that improve immune response against the virus.
Low Vitamin D Linked to Greater Hepatitis B Virus Replication
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- Category: HBV Disease Progression
- Published on Thursday, 13 June 2013 00:00
- Written by Liz Highleyman
Low blood levels of 25-hydroxyvitamin D were strongly associated with higher hepatitis B virus (HBV) viral load in a study of more than 200 untreated patients described in the May 22, 2013 advance online edition of Hepatology.
Korean Mummy Reveals Hepatitis B Genetic Clues
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- Category: HBV Basic Science
- Published on Wednesday, 30 May 2012 00:00
- Written by Press Release
Genetic analysis of a liver sample from a mummified child found in Korea has revealed a distinct ancient form of a hepatitis B virus C2 genotype now common in Southeast Asia, researchers reported in the May 21, 2012, advance online edition of Hepatology.
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