Neurocognitive Problems
IAS 2015: HIV+ People with Asymptomatic Cognitive Impairment More Likely to Develop Symptoms
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- Category: Neurocognitive Problems
- Published on Thursday, 20 August 2015 00:00
- Written by Liz Highleyman
People with HIV who showed evidence of asymptomatic neurocognitive impairment at study entry were nearly twice as likely to progress to symptomatic HIV-associated neurocognitive disorders than those with initially normal neuropsychological tests, according to research presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last month in Vancouver.
HIV May Cause Cognitive Impairment by Disrupting Brain's Garbage Disposal
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- Category: Neurocognitive Problems
- Published on Thursday, 05 February 2015 00:00
- Written by UCSD
HIV's Tat protein interferes with autophagy, a process by which damaged or unneeded cell components are broken down and eliminated, according to research published in the February 4 Journal of Neuroscience. This disruption can lead to neuron damage, but the immunosuppressant drug rapamycin was able to reverse this process in a study of mice.
CROI 2014: Neurocognitive Problems, Depression, and Early ART in People with HIV
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- Category: Neurocognitive Problems
- Published on Tuesday, 08 April 2014 00:00
- Written by Matt Sharp
In a particularly challenging area of HIV care where research is complicated by gaps in knowledge and invasive clinical procedures, there was significant attention to neurological manifestations -- or neuroAIDS -- at this year’s Conference on Antiretroviral Agents and Chemotherapy (CROI 2014) last month in Boston.
AIDS2014: Efavirenz Use Not Linked to Neurocognitive Impairment, Study Finds
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- Category: Neurocognitive Problems
- Published on Thursday, 24 July 2014 00:00
- Written by Liz Highleyman
People who use antiretroviral regimens containing efavirenz (Sustiva, also in the Atripla coformulation) were not at higher risk for impaired neurocognitive function, either overall or when looking at specific functional domain, researchers reported this week at the 20th International AIDS Conference in Melbourne, Australia.
EACS 2013: Suicide Rates and Psychiatric Drug Use Among People with HIV
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- Category: Neurocognitive Problems
- Published on Wednesday, 30 October 2013 00:00
- Written by Gus Cairns
A study presented at the recent 14th European AIDS Conference found that the suicide rate among people with HIV in British Columbia had fallen 35-fold since 1996 and was now close to that of the general population. However, a second study from Denmark found rates of psychiatric drug use, especially sleeping pills and tranquilizers, to be 2-3 times higher among people with HIV than in the general population, and saw a marked rise in the use of antipsychotic drugs 7 or 8 years after diagnosis.